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Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint

Cdc2p is a cyclin-dependent kinase (CDK) essential for both mitotic and meiotic cell cycle progression in fission yeast. We have found that the spindle checkpoint kinase Bub1p becomes phosphorylated by Cdc2p during spindle damage in mitotic cells. Cdc2p directly phosphorylates Bub1p in vitro at the...

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Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Yamaguchi, Satoko, Decottignies, Anabelle, Nurse, Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12606573/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg100
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