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Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint

Cdc2p is a cyclin-dependent kinase (CDK) essential for both mitotic and meiotic cell cycle progression in fission yeast. We have found that the spindle checkpoint kinase Bub1p becomes phosphorylated by Cdc2p during spindle damage in mitotic cells. Cdc2p directly phosphorylates Bub1p in vitro at the...

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Vydáno v:EMBO J
Hlavní autoři: Yamaguchi, Satoko, Decottignies, Anabelle, Nurse, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12606573/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg100
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