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Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint

Cdc2p is a cyclin-dependent kinase (CDK) essential for both mitotic and meiotic cell cycle progression in fission yeast. We have found that the spindle checkpoint kinase Bub1p becomes phosphorylated by Cdc2p during spindle damage in mitotic cells. Cdc2p directly phosphorylates Bub1p in vitro at the...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Yamaguchi, Satoko, Decottignies, Anabelle, Nurse, Paul
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2003
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12606573/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg100
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