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Ionizing radiation induces caspase-dependent but Chk2- and p53-independent cell death in Drosophila melanogaster
Ionizing radiation (IR) can induce apoptosis via p53, which is the most commonly mutated gene in human cancers. Loss of p53, however, can render cancer cells refractory to therapeutic effects of IR. Alternate p53-independent pathways exist but are not as well understood as p53-dependent apoptosis. S...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502560/ https://ncbi.nlm.nih.gov/pubmed/16785441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510528103 |
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