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Distinct structural and mechanical properties of the nuclear lamina in Hutchinson–Gilford progeria syndrome
The nuclear lamina is a network of structural filaments, the A and B type lamins, located at the nuclear envelope and throughout the nucleus. Lamin filaments provide the nucleus with mechanical stability and support many basic activities, including gene regulation. Mutations in LMNA, the gene encodi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502447/ https://ncbi.nlm.nih.gov/pubmed/16801550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601058103 |
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