Identification of high excision capacity for 5-hydroxymethyluracil mispaired with guanine in DNA of Escherichia coli MutM, Nei and Nth DNA glycosylases

The oxidation and deamination of 5-methylcytosine (5mC) in DNA generates a base-pair between 5-hydroxymethyluracil (5hmU) and guanine. 5hmU normally forms a base-pair with adenine. Therefore, the conversion of 5mC to 5hmU is a potential pathway for the generation of 5mC to T transitions. Mammalian c...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hori, Masaki, Yonei, Shuji, Sugiyama, Hiroshi, Kino, Katsuhito, Yamamoto, Kazuo, Zhang, Qiu-Mei
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2003
Materias:
Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC150241/
https://ncbi.nlm.nih.gov/pubmed/12582238
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares