Structure of Golgi α-mannosidase II: a target for inhibition of growth and metastasis of cancer cells

Golgi α-mannosidase II, a key enzyme in N-glycan processing, is a target in the development of anti- cancer therapies. The crystal structure of Drosophila Golgi α-mannosidase II in the absence and presence of the anti-cancer agent swainsonine and the inhibitor deoxymannojirimycin reveals a novel pro...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	EMBO J
Autori principali:	van den Elsen, Jean M.H., Kuntz, Douglas A., Rose, David R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11406577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.12.3008
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!