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Golgi Alpha1,2-Mannosidase IA Promotes Efficient Endoplasmic Reticulum-Associated Degradation of NKCC2

Mutations in the apically located kidney Na-K-2Cl cotransporter NKCC2 cause type I Bartter syndrome, a life-threatening kidney disorder. We previously showed that transport from the ER represents the limiting phase in NKCC2 journey to the cell surface. Yet very little is known about the ER quality c...

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Bibliografiska uppgifter
Huvudupphov: Sylvie Demaretz, Elie Seaayfan, Dalal Bakhos-Douaihy, Nadia Frachon, Martin Kömhoff, Kamel Laghmani
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2021-12-01
Serie:Cells
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Länkar:https://www.mdpi.com/2073-4409/11/1/101
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