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Ancient ubiquitous protein 1 (AUP1) is a prognostic biomarker connected with TP53 mutation and the inflamed microenvironments in glioma

Abstract Introduction Glioblastoma (GBM) is the most common and lethal brain tumor. The current treatment is surgical removal combined with radiotherapy and chemotherapy, Temozolomide (TMZ). However, tumors tend to develop TMZ resistance which leads to therapeutic failure. Ancient ubiquitous protein...

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Principais autores: Pei-Chi Chang, Yu-Chieh Lin, Hui-Ju Yen, Dueng-Yuan Hueng, Shih-Ming Huang, Yao-Feng Li
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-04-01
coleção:Cancer Cell International
Assuntos:
AUP1
Glioblastoma
TP53
TCGA
CGGA
GLASS
Acesso em linha:https://doi.org/10.1186/s12935-023-02912-y
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