Overexpression of Dimethylarginine Dimethylaminohydrolase Enhances Tumor Hypoxia: An Insight into the Relationship of Hypoxia and Angiogenesis In Vivo

The oxygenation status of tumors derived from wild-type C6 glioma cells and clone D27 cells overexpressing dimethylarginine dimethylaminohydrolase (DDAH) was assessed in vivo using a variety of direct and indirect assays of hypoxia. Clone D27 tumors exhibit a more aggressive and better-vascularized...

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Autors principals: Kostourou, Vassiliki, Troy, Helen, Murray, Joanne F., Cullis, Elizabeth R., Whitley, Guy St. J., Griffiths, John R., Robinson, Simon P.
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2004
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502106/
https://ncbi.nlm.nih.gov/pubmed/15256062
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