A Novel Method for Imaging Apoptosis Using a Caspase-1 Near-Infrared Fluorescent Probe

Here we describe a novel method for imaging apoptosis in cells using a near-infrared fluorescent (NIRF) probe selective for caspase-1 (interleukin 1β-converting enzyme, ICE). This biocompatible, optically quenched ICE-NIRF probe incorporates a peptide substrate, which can be selectively cleaved by c...

Full description

Saved in:
Bibliographic Details
Main Authors: Messerli, Shanta M, Prabhakar, Shilpa, Tang, Yi, Shah, Khalid, Cortes, Maria L, Murthy, Vidya, Weissleder, Ralph, Breakefield, Xandra O, Tung, Ching-Hsuan
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502090/
https://ncbi.nlm.nih.gov/pubmed/15140398
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items