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Near-infrared fluorescent imaging of matrix metalloproteinase activity following myocardial infarction

We used a molecular probe activated by protease cleavage to image expression of matrix metalloproteinases (MMPs) in the heart following myocardial infarction. METHODS AND RESULTS: We synthesized and characterized a near-infrared fluorescent (NIRF) probe that is activated by proteolytic cleavage by M...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Jiqiu, Tung, Ching-Hsuan, Allport, Jennifer R., Chen, Si, Weissleder, Ralph, Huang, Paul L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733536/
https://ncbi.nlm.nih.gov/pubmed/15809374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000160936.91849.9F
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