Optimal Classes of Chemotherapeutic Agents Sensitized by Specific Small-Molecule Inhibitors of Akt In Vitro and In Vivo

Akt is a serine/threonine kinase that transduces survival signals from survival/growth factors. Deregulation and signal imbalance in cancer cells make them prone to apoptosis. Upregulation or activation of Akt to aid the survival of cancer cells is a common theme in human malignancies. We have devel...

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書誌詳細
主要な著者: Shi, Yan, Liu, Xuesong, Han, Edward K., Guan, Ran, Shoemaker, Alexander R., Oleksijew, Anatol, Woods, Keith W., Fisher, John P., Klinghofer, Vered, Lasko, Loren, McGonigal, Thomas, Li, Qun, Rosenberg, Saul H., Giranda, Vincent L., Luo, Yan
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press, Inc. 2005
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502019/
https://ncbi.nlm.nih.gov/pubmed/16331885
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