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Accelerated Degradation of Caspase-8 Protein Correlates with TRAIL Resistance in a DLD1 Human Colon Cancer Cell Line

The tumor-selective cytotoxic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) makes TRAIL an attractive candidate as an anticancer agent. However, resistance to TRAIL poses a challenge in anticancer therapy with TRAIL. Therefore, characterizing the mechanisms of resistance...

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Detalhes bibliográficos
Main Authors: Zhang, Lidong, Zhu, Hongbo, Teraishi, Fuminori, Davis, John J, Guo, Wei, Fan, Zhen, Fang, Bingliang
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501285/
https://ncbi.nlm.nih.gov/pubmed/16036110
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