Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines

The discovery of cancer cell-selective tumour necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis generated broad excitement and development of TRAIL receptor agonists (TRA) as potential cancer therapy. Studies demonstrating the synergistic combination effect of SMAC mimetics...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Polanski, R, Vincent, J, Polanska, U M, Petreus, T, Tang, E K Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632282/
https://ncbi.nlm.nih.gov/pubmed/26426685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.234
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