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Design of Antisense RNA Constructs for Downregulation of the Acetone Formation Pathway of Clostridium acetobutylicum

We investigated the effect of antisense RNA (asRNA) structural properties on the downregulation efficacy of enzymes in the acetone-formation pathway (acetoacetate decarboxylase [AADC] and coenzyme A-transferase [CoAT]) of Clostridium acetobutylicum strain ATCC 824. First, we generated three strains,...

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Hlavní autoři: Tummala, Seshu B., Welker, Neil E., Papoutsakis, Eleftherios T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150123/
https://ncbi.nlm.nih.gov/pubmed/12618456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.6.1923-1934.2003
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