Design of Antisense RNA Constructs for Downregulation of the Acetone Formation Pathway of Clostridium acetobutylicum

We investigated the effect of antisense RNA (asRNA) structural properties on the downregulation efficacy of enzymes in the acetone-formation pathway (acetoacetate decarboxylase [AADC] and coenzyme A-transferase [CoAT]) of Clostridium acetobutylicum strain ATCC 824. First, we generated three strains,...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Tummala, Seshu B., Welker, Neil E., Papoutsakis, Eleftherios T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12618456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.6.1923-1934.2003
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