Antisense RNA Downregulation of Coenzyme A Transferase Combined with Alcohol-Aldehyde Dehydrogenase Overexpression Leads to Predominantly Alcohologenic Clostridium acetobutylicum Fermentations

Plasmid pAADB1 for the overexpression of the alcohol-aldehyde dehydrogenase (aad) gene and downregulation of the coenzyme A transferase (CoAT) using antisense RNA (asRNA) against ctfB (the second CoAT gene on the polycistronic aad-ctfA-ctfB message) was used in order to increase the butanol/acetone...

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Bibliografiska uppgifter
Huvudupphovsmän: Tummala, Seshu B., Junne, Stefan G., Papoutsakis, Eleftherios T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Genetics and Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC156216/
https://ncbi.nlm.nih.gov/pubmed/12775702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.12.3644-3653.2003
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