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Antisense RNA Strategies for Metabolic Engineering of Clostridium acetobutylicum

We examined the effectiveness of antisense RNA (as RNA) strategies for metabolic engineering of Clostridium acetobutylicum. Strain ATCC 824(pRD4) was developed to produce a 102-nucleotide asRNA with 87% complementarity to the butyrate kinase (BK) gene. Strain ATCC 824(pRD4) exhibited 85 to 90% lower...

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Bibliografische gegevens
Hoofdauteurs: Desai, Ruchir P., Papoutsakis, Eleftherios T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC91126/
https://ncbi.nlm.nih.gov/pubmed/10049845
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