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A Specific Inhibitor of TGF-β Receptor Kinase, SB-431542, as a Potent Antitumor Agent for Human Cancers

Small molecule inhibitors of signaling pathways have proven to be extremely useful for the development of therapeutic strategies for human cancers. Blocking the tumor-promoting effects of transforming growth factor-β (TGF-β) in advanced stage carcinogenesis provides a potentially interesting drug ta...

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Détails bibliographiques
Auteurs principaux: Halder, Sunil K, Beauchamp, R Daniel, Datta, Pran K
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press Inc. 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501161/
https://ncbi.nlm.nih.gov/pubmed/15967103
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