TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis

Rotator cuff tears represent a large burden of muscle-tendon injuries in our aging population. While small tears can be repaired surgically with good outcomes, critical size tears are marked by muscle atrophy, fibrosis, and fatty infiltration, which can lead to failed repair, frequent re-injury, and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Davies, Michael R., Liu, Xuhui, Lee, Lawrence, Laron, Dominique, Ning, Anne Y., Kim, Hubert T., Feeley, Brian T.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871364/
https://ncbi.nlm.nih.gov/pubmed/27186977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155486
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