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TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis

Rotator cuff tears represent a large burden of muscle-tendon injuries in our aging population. While small tears can be repaired surgically with good outcomes, critical size tears are marked by muscle atrophy, fibrosis, and fatty infiltration, which can lead to failed repair, frequent re-injury, and...

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書誌詳細
出版年:PLoS One
主要な著者: Davies, Michael R., Liu, Xuhui, Lee, Lawrence, Laron, Dominique, Ning, Anne Y., Kim, Hubert T., Feeley, Brian T.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871364/
https://ncbi.nlm.nih.gov/pubmed/27186977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155486
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