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Antisense-Mediated Suppression of Heparanase Gene Inhibits Melanoma Cell Invasion

Cancer metastasis is a frequent manifestation of malignant melanoma progression. Successful invasion into distant organs by tumor cells must include attachment to microvessel endothelial cells, and degradation of basement membranes and extracellular matrix (ECM). Heparan sulfate proteoglycans (HSPG)...

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Bibliographische Detailangaben
Hauptverfasser: Roy, Madhuchhanda, Reiland, Jane, Murry, Brian P, Chouljenko, Vladimir, Kousoulas, Konstantin G, Marchetti, Dario
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501137/
https://ncbi.nlm.nih.gov/pubmed/15799825
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