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Cell Surface Heparan Sulfate Released by Heparanase Promotes Melanoma Cell Migration and Angiogenesis

Heparan sulfate proteoglycans are essential components of the cell-surface and extracellular matrix which provide structural integrity and act as storage depots for growth factors and chemokines, through their heparan sulfate (HS) side chains. Heparanase is the only mammalian endoglycosidase known t...

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Detalhes bibliográficos
Main Authors: Roy, Madhuchhanda, Marchetti, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736788/
https://ncbi.nlm.nih.gov/pubmed/19115257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22005
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