Bone Microenvironment Modulates Expression and Activity of Cathepsin B in Prostate Cancer

Prostate cancers metastasize to bone leading to osteolysis. Here we assessed proteolysis of DQ-collagen I (a bone matrix protein) and, for comparison, DQ-collagen IV, by living human prostate carcinoma cells in vitro. Both collagens were degraded, and this degradation was reduced by inhibitors of ma...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Podgorski, Izabela, Linebaugh, Bruce E, Sameni, Mansoureh, Jedeszko, Christopher, Bhagat, Sunita, Cher, Michael L, Sloane, Bonnie F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2005
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501133/
https://ncbi.nlm.nih.gov/pubmed/15799821
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi