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Bone Marrow-Derived Cathepsin K Cleaves SPARC in Bone Metastasis
Bone metastasis is a hallmark of advanced prostate and breast cancers, yet the critical factors behind attraction of tumors to the skeleton have not been validated. Here, we investigated the involvement of cathepsin K in the progression of prostate tumors in the bone, which occurs both by direct deg...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Investigative Pathology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731144/ https://ncbi.nlm.nih.gov/pubmed/19700761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080906 |
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