Bone Marrow-Derived Cathepsin K Cleaves SPARC in Bone Metastasis

Bone metastasis is a hallmark of advanced prostate and breast cancers, yet the critical factors behind attraction of tumors to the skeleton have not been validated. Here, we investigated the involvement of cathepsin K in the progression of prostate tumors in the bone, which occurs both by direct deg...

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Main Authors: Podgorski, Izabela, Linebaugh, Bruce E., Koblinski, Jennifer E., Rudy, Deborah L., Herroon, Mackenzie K., Olive, Mary B., Sloane, Bonnie F.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2009
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Regular Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731144/
https://ncbi.nlm.nih.gov/pubmed/19700761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080906
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