Antigenic Hepatitis A Virus Structures May Be Produced in Escherichia coli

The synthesis of 14S pentamers and 70S empty capsids of hepatitis A virus (HAV) has been accomplished by expressing the viral genome for periods of time longer than 4 h in Escherichia coli. HAV pentamers (14S) self-assembled into capsids (70S) in vitro. The antibodies induced by these structures rec...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Sánchez, Glòria, Caballero, Santiago, Guix, Susana, Bosch, Albert, Pintó, Rosa M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Physiology and Biotechnology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12620879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.3.1840-1843.2003
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