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Antigenic Hepatitis A Virus Structures May Be Produced in Escherichia coli
The synthesis of 14S pentamers and 70S empty capsids of hepatitis A virus (HAV) has been accomplished by expressing the viral genome for periods of time longer than 4 h in Escherichia coli. HAV pentamers (14S) self-assembled into capsids (70S) in vitro. The antibodies induced by these structures rec...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150110/ https://ncbi.nlm.nih.gov/pubmed/12620879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.3.1840-1843.2003 |
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