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Protease nexin-1 expression is altered in human breast cancer

BACKGROUND: Urokinase-type Plasminogen Activator (uPA), a serine protease, plays a pivotal role in human breast cancer metastasis by mediating the degradation of extracellular matrix proteins and promoting cell motility. In more advanced breast cancers, uPA activity is significantly up regulated and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Candia, Britny J, Hines, William C, Heaphy, Christopher M, Griffith, Jeffrey K, Orlando, Robert A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501059/
https://ncbi.nlm.nih.gov/pubmed/16737540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-6-16
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