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Human fibroblasts accelerate the inhibition of thrombin by protease nexin.

Protease nexin (PN) is a protein protease inhibitor secreted by human fibroblasts in culture that complexes and inhibits certain regulatory serine proteases. The PN-protease complexes then bind to these cells and are rapidly internalized and degraded. This report shows that the fibroblast surface ac...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Farrell, D H, Cunningham, D D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3462733/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.18.6858
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