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A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death.

Protease nexin I (PNI) is a member of the family of serine protease inhibitors (serpins) that have been shown to promote neurite outgrowth in vitro from different neuronal cell types. These include neuroblastoma cells, hippocampal neurons, and sympathetic neurons. Free PNI protein is markedly decrea...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Houenou, L J, Turner, P L, Li, L, Oppenheim, R W, Festoff, B W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42727/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.895
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