Protease nexin-1 expression is altered in human breast cancer

BACKGROUND: Urokinase-type Plasminogen Activator (uPA), a serine protease, plays a pivotal role in human breast cancer metastasis by mediating the degradation of extracellular matrix proteins and promoting cell motility. In more advanced breast cancers, uPA activity is significantly up regulated and...

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Detalhes bibliográficos
Main Authors: Candia, Britny J, Hines, William C, Heaphy, Christopher M, Griffith, Jeffrey K, Orlando, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501059/
https://ncbi.nlm.nih.gov/pubmed/16737540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-6-16
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