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Drosophila CENP-A Mutations Cause a BubR1- Dependent Early Mitotic Delay without Normal Localization of Kinetochore Components

The centromere/kinetochore complex plays an essential role in cell and organismal viability by ensuring chromosome movements during mitosis and meiosis. The kinetochore also mediates the spindle attachment checkpoint (SAC), which delays anaphase initiation until all chromosomes have achieved bipolar...

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Detalles Bibliográficos
Main Authors: Blower, Michael D, Daigle, Tanya, Kaufman, Thom, Karpen, Gary H
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500813/
https://ncbi.nlm.nih.gov/pubmed/16839185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020110
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