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Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel

β-Adrenergic receptor stimulation increases heart rate and shortens ventricular action-potential duration, the latter effect due in part to a cAMP-dependent increase in the slow outward potassium current (I(Ks)). Mutations in either KCNQ1 or KCNE1, the I(Ks) subunits, are associated with variants (L...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kurokawa, Junko, Chen, Lei, Kass, Robert S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC149969/
https://ncbi.nlm.nih.gov/pubmed/12566567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0434935100
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