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Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel
β-Adrenergic receptor stimulation increases heart rate and shortens ventricular action-potential duration, the latter effect due in part to a cAMP-dependent increase in the slow outward potassium current (I(Ks)). Mutations in either KCNQ1 or KCNE1, the I(Ks) subunits, are associated with variants (L...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149969/ https://ncbi.nlm.nih.gov/pubmed/12566567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0434935100 |
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