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An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

The water channel AQP4 is concentrated in perivascular and subpial membrane domains of brain astrocytes. These membranes form the interface between the neuropil and extracerebral liquid spaces. AQP4 is anchored at these membranes by its carboxyl terminus to α-syntrophin, an adapter protein associate...

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Gorde:
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Amiry-Moghaddam, Mahmood, Otsuka, Takashi, Hurn, Patricia D., Traystman, Richard J., Haug, Finn-Mogens, Froehner, Stanley C., Adams, Marvin E., Neely, John D., Agre, Peter, Ottersen, Ole Petter, Bhardwaj, Anish
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149966/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12578959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437946100
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