An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

The water channel AQP4 is concentrated in perivascular and subpial membrane domains of brain astrocytes. These membranes form the interface between the neuropil and extracerebral liquid spaces. AQP4 is anchored at these membranes by its carboxyl terminus to α-syntrophin, an adapter protein associate...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Amiry-Moghaddam, Mahmood, Otsuka, Takashi, Hurn, Patricia D., Traystman, Richard J., Haug, Finn-Mogens, Froehner, Stanley C., Adams, Marvin E., Neely, John D., Agre, Peter, Ottersen, Ole Petter, Bhardwaj, Anish
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2003
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12578959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437946100
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