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Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

Streptococcus pneumoniae is one of the leading causes of invasive bacterial disease worldwide. Fragments of the cell wall and the cytolytic toxin pneumolysin have been shown to contribute substantially to inflammatory damage, although the interactions between pneumococcal components and host-cell st...

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Autores principales: Malley, Richard, Henneke, Philipp, Morse, Sarah C., Cieslewicz, Michael J., Lipsitch, Marc, Thompson, Claudette M., Kurt-Jones, Evelyn, Paton, James C., Wessels, Michael R., Golenbock, Douglas T.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC149942/
https://ncbi.nlm.nih.gov/pubmed/12569171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0435928100
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