Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

Streptococcus pneumoniae is one of the leading causes of invasive bacterial disease worldwide. Fragments of the cell wall and the cytolytic toxin pneumolysin have been shown to contribute substantially to inflammatory damage, although the interactions between pneumococcal components and host-cell st...

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Detalhes bibliográficos
Main Authors: Malley, Richard, Henneke, Philipp, Morse, Sarah C., Cieslewicz, Michael J., Lipsitch, Marc, Thompson, Claudette M., Kurt-Jones, Evelyn, Paton, James C., Wessels, Michael R., Golenbock, Douglas T.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149942/
https://ncbi.nlm.nih.gov/pubmed/12569171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0435928100
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