Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection

No transgenic cystic fibrosis (CF) mouse model developed to date mimics the major clinical phenotype found in humans with CF, chronic Pseudomonas aeruginosa lung infection. In a transgenic CF transmembrane conductance regulator (cftr) mouse colony, we found WT, heterozygous, and homozygous CF mice h...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Coleman, Fadie T., Mueschenborn, Simone, Meluleni, Gloria, Ray, Christopher, Carey, Vincent J., Vargas, Sara O., Cannon, Carolyn L., Ausubel, Frederick M., Pier, Gerald B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12578988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437901100
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