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Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats
There is a concern that increased paternal age may be associated with altered fertility and an increased incidence of birth defects in man. In previous studies of aged male rats, we have found abnormalities in the fertility and in the embryos sired by older males. Aging in mammals is associated with...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149909/ https://ncbi.nlm.nih.gov/pubmed/12574505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437971100 |
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