Exonucleolytic degradation of double-stranded RNA by an activity in Xenopus laevis germinal vesicles

We have identified, in extracts from Xenopus laevis germinal vesicles, a 5′ exonuclease activity that cleaves double-stranded RNA (dsRNA). Features of the 5′ ends of dsRNAs determine whether the strands are symmetrically or asymmetrically degraded. The activity hydrolyzes in the 5′ to 3′ direction,...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Fruscoloni, Paolo, Zamboni, Michela, Baldi, M. Irene, Tocchini-Valentini, Glauco P.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2003
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12578969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252777499
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