Exonucleolytic degradation of double-stranded RNA by an activity in Xenopus laevis germinal vesicles

We have identified, in extracts from Xenopus laevis germinal vesicles, a 5′ exonuclease activity that cleaves double-stranded RNA (dsRNA). Features of the 5′ ends of dsRNAs determine whether the strands are symmetrically or asymmetrically degraded. The activity hydrolyzes in the 5′ to 3′ direction,...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Fruscoloni, Paolo, Zamboni, Michela, Baldi, M. Irene, Tocchini-Valentini, Glauco P.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2003
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12578969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252777499
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