Exonucleolytic degradation of double-stranded RNA by an activity in Xenopus laevis germinal vesicles

We have identified, in extracts from Xenopus laevis germinal vesicles, a 5′ exonuclease activity that cleaves double-stranded RNA (dsRNA). Features of the 5′ ends of dsRNAs determine whether the strands are symmetrically or asymmetrically degraded. The activity hydrolyzes in the 5′ to 3′ direction,...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Fruscoloni, Paolo, Zamboni, Michela, Baldi, M. Irene, Tocchini-Valentini, Glauco P.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 2003
Aiheet:	Biological Sciences
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12578969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252777499
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