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Exonucleolytic degradation of double-stranded RNA by an activity in Xenopus laevis germinal vesicles

We have identified, in extracts from Xenopus laevis germinal vesicles, a 5′ exonuclease activity that cleaves double-stranded RNA (dsRNA). Features of the 5′ ends of dsRNAs determine whether the strands are symmetrically or asymmetrically degraded. The activity hydrolyzes in the 5′ to 3′ direction,...

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Hlavní autoři: Fruscoloni, Paolo, Zamboni, Michela, Baldi, M. Irene, Tocchini-Valentini, Glauco P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC149885/
https://ncbi.nlm.nih.gov/pubmed/12578969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252777499
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