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PECAM-1/CD31 Trans-homophilic Binding at the Intercellular Junctions Is Independent of Its Cytoplasmic Domain; Evidence for Heterophilic Interaction with Integrin αvβ3 in Cis

PECAM-1/CD31 is a cell adhesion and signaling molecule that is enriched at the endothelial cell junctions. Alternative splicing generates multiple PECAM-1 splice variants, which differ in their cytoplasmic domains. It has been suggested that the extracellular ligand-binding property, homophilic vers...

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Detalhes bibliográficos
Main Authors: Wong, Cindy W.Y., Wiedle, Guido, Ballestrem, Christoph, Wehrle-Haller, Bernhard, Etteldorf, Susanne, Bruckner, Monika, Engelhardt, Britta, Gisler, Roland H., Imhof, Beat A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14979/
https://ncbi.nlm.nih.gov/pubmed/10982404
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