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Temperature-Dependent Conformational Changes in Herpes Simplex Virus ICP4 That Affect Transcription Activation

The C-terminal 500 amino acids of herpes simplex virus type 1 ICP4 are required for full activator function and viral growth and are known to participate in interactions consistent with the role of ICP4 as an activator of transcription. Oligonucleotide mutagenesis was used to target stretches of ami...

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Hlavní autoři: Compel, Peter, DeLuca, Neal A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC149779/
https://ncbi.nlm.nih.gov/pubmed/12584349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.3257-3268.2003
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