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Structures of Rotavirus Reassortants Demonstrate Correlation of Altered Conformation of the VP4 Spike and Expression of Unexpected VP4-Associated Phenotypes

Numerous prior studies have indicated that viable rotavirus reassortants containing structural proteins of heterologous parental origin may express unexpected phenotypes, such as changes in infectivity and immunogenicity. To provide a structural basis for alterations in phenotypic expression, a thre...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Pesavento, Joseph B., Billingsley, Angela M., Roberts, Ed J., Ramig, Robert F., Prasad, B. V. Venkataram
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12584352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.5.3291-3296.2003
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