Structures of Rotavirus Reassortants Demonstrate Correlation of Altered Conformation of the VP4 Spike and Expression of Unexpected VP4-Associated Phenotypes

Numerous prior studies have indicated that viable rotavirus reassortants containing structural proteins of heterologous parental origin may express unexpected phenotypes, such as changes in infectivity and immunogenicity. To provide a structural basis for alterations in phenotypic expression, a thre...

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Detalhes bibliográficos
Main Authors: Pesavento, Joseph B., Billingsley, Angela M., Roberts, Ed J., Ramig, Robert F., Prasad, B. V. Venkataram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149743/
https://ncbi.nlm.nih.gov/pubmed/12584352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.3291-3296.2003
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