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Interactions between the Transmembrane Segments of the Alphavirus E1 and E2 Proteins Play a Role in Virus Budding and Fusion

The alphavirus envelope is built by heterodimers of the membrane proteins E1 and E2. The complex is formed as a p62E1 precursor in the endoplasmic reticulum. During transit to the plasma membrane (PM), it is cleaved into mature E1-E2 heterodimers, which are oligomerized into trimeric complexes, so-c...

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Autores principales: Sjöberg, Mathilda, Garoff, Henrik
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC149539/
https://ncbi.nlm.nih.gov/pubmed/12610119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3441-3450.2003
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