Protein Synthesis and Endoplasmic Reticulum Stress Can Be Modulated by the Hepatitis C Virus Envelope Protein E2 through the Eukaryotic Initiation Factor 2α Kinase PERK

The hepatitis C virus envelope protein, E2, is an endoplasmic reticulum (ER)-bound protein that contains a region of sequence homology with the double-stranded RNA-activated protein kinase PKR and its substrate, the eukaryotic translation initiation factor 2 (eIF2). We previously reported that E2 mo...

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Detalles Bibliográficos
Main Authors: Pavio, Nicole, Romano, Patrick R., Graczyk, Thomas M., Feinstone, Stephen M., Taylor, Deborah R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC149509/
https://ncbi.nlm.nih.gov/pubmed/12610133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3578-3585.2003
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