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T Cells Infiltrate the Brain in Murine and Human Transmissible Spongiform Encephalopathies

CD4 and CD8 T lymphocytes infiltrate the parenchyma of mouse brains several weeks after intracerebral, intraperitoneal, or oral inoculation with the Chandler strain of mouse scrapie, a pattern not seen with inoculation of prion protein knockout (PrP(−/−)) mice. Associated with this cellular infiltra...

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Lewicki, Hanna, Tishon, Antoinette, Homann, Dirk, Mazarguil, Honoré, Laval, Françoise, Asensio, Valerie C., Campbell, Iain L., DeArmond, Stephen, Coon, Bryan, Teng, Chao, Gairin, Jean Edouard, Oldstone, Michael B. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12610154/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.6.3799-3808.2003
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