T Cells Infiltrate the Brain in Murine and Human Transmissible Spongiform Encephalopathies

CD4 and CD8 T lymphocytes infiltrate the parenchyma of mouse brains several weeks after intracerebral, intraperitoneal, or oral inoculation with the Chandler strain of mouse scrapie, a pattern not seen with inoculation of prion protein knockout (PrP(−/−)) mice. Associated with this cellular infiltra...

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Detalhes bibliográficos
Main Authors: Lewicki, Hanna, Tishon, Antoinette, Homann, Dirk, Mazarguil, Honoré, Laval, Françoise, Asensio, Valerie C., Campbell, Iain L., DeArmond, Stephen, Coon, Bryan, Teng, Chao, Gairin, Jean Edouard, Oldstone, Michael B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149501/
https://ncbi.nlm.nih.gov/pubmed/12610154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3799-3808.2003
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